Evaluating kratom alkaloids using PHASE | PLOS ONE
An updated assessment of the translational promise of G-protein-biased kappa opioid receptor agonists to treat pain and other indications without debilitating adverse effects - ScienceDirect
Medicines | Free Full-Text | Mitragyna speciosa: Clinical, Toxicological Aspects and Analysis in Biological and Non-Biological Samples
Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom | ACS Chemical Neuroscience
Pharmaceutics | Free Full-Text | Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects | ACS Central Science
Mitragynine - Wikipedia
Kappa Opioid Receptor Structure Revealed, A Potential Milestone in Medication Development | National Institute on Drug Abuse (NIDA)
Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse | National Institute on Drug Abuse (NIDA)
The science behind kratom's strange leaves
Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience
Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom | ACS Chemical Neuroscience
Scientists Just Solved a Major Piece of the Opioid Puzzle | WIRED
Opioid-based plant might not be best solution for those seeking to curb habitual alcohol use - Purdue University News
Site selective C–H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy | Nature Communications
Kratom - Proteopedia, life in 3D
G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder - Gutridge - 2020 - British Journal of Pharmacology - Wiley Online Library
Central nervous system receptor binding data for mitragynine.... | Download Table
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions | Scientific Reports
Kratom | National Institute on Drug Abuse (NIDA)
Evaluating kratom alkaloids using PHASE | PLOS ONE
A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects | Journal of Medicinal Chemistry
Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse | National Institute on Drug Abuse (NIDA)
The medicinal chemistry and neuropharmacology of kratom: A preliminary discussion of a promising medicinal plant and analysis of its potential for abuse - ScienceDirect
Recreational Drug Kratom Hits the Same Brain Receptors as Strong Opioids - Scientific American
